[No authors listed]
In pre-aggregation amoebae of Dictyostelium discoideum, phenotypic differences with respect to cellular Ca2+ and cell cycle phases are known to bias post-aggregative cell-type choice. Using chlortetracycline fluorescence as an indicator, we found that cellular Ca2+ is highest at the S phase of the cell cycle. Upon increasing the level of Ca2+ with the help of the calcium ionophore A23187, there is a significant decrease in the cyclin B (clb1) mRNA level; the cdc2 mRNA level shows a marginal decrease. These results suggest that the effect of Ca2+ and the cell cycle on cell fate could be exerted at the level of transcription, or message stability, of specific genes.
KEYWORDS: {{ getKeywords(articleDetailText.words) }}
Sample name | Organism | Experiment title | Sample type | Library instrument | Attributes | |||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
{{attr}} | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{ dataList.sampleTitle }} | {{ dataList.organism }} | {{ dataList.expermentTitle }} | {{ dataList.sampleType }} | {{ dataList.libraryInstrument }} | {{ showAttributeName(index,attr,dataList.attributes) }} |
{{ list.authorName }} {{ list.authorName }} |