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Cloning and sequencing of the cDNA encoding human neurotrypsin.

Biochim. Biophys. Acta. 1998 Mar 09;1396(2):143-7
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摘要


cDNA clones encoding human neurotrypsin have been isolated from a human fetal brain cDNA library using a PCR-amplified probe. The assembled cDNA sequence contains a 2625 bp open reading frame encoding a multidomain serine protease with an overall sequence identity of 82.5% to murine neurotrypsin. Surprisingly, the human neurotrypsin exhibits an additional scavenger receptor cysteine-rich repeat.

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