Genomic structure of the maize TATA-box binding protein 1 (TBP-1): conserved exon/intron structure in eukaryotic TBP genes.
[No authors listed]
摘要
The gene system of the TATA-box binding protein (TBP) is well suited for the study of the evolutionary conservation of essential components of eukaryotic transcription initiation. In this context we have isolated and sequenced the maize TBP gene for a comparison with TBP genes from other organisms. In particular, a molecular phylogenetic analysis of the exon/intron structure of these genes including the archaeal TBP homolog (Thermococcus celer) was performed, revealing that the intron insertion probably occurred after the early appearance of the characteristic tandem repeat within the highly conserved C-terminal domain of all known TBPs, but before separation of the eukaryotic progenitor into the different kingdoms.
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基因功能
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原始数据
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文献解读
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