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Cloning of a putative gamma-aminobutyric acid (GABA) receptor subunit rho 3 cDNA.

Biochim. Biophys. Acta. 1996 Feb 07;1305(1-2):15-8
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摘要


Cloned cDNA encoding a putative member of GABA receptor rho-subunit class was isolated from rat-retina-mRNA-derived libraries. The cDNA encodes a signal peptide of 21 amino acids followed by the mature rho 3 subunit sequence of 443 amino acids. The proposed amino acid sequence exhibits 63 and 61% homology to the previously-reported human rho 1 and rat rho 2 sequences, respectively. Northern blot analysis demonstrated the expression of mRNA for rho 3 subunit in retina.

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