例如:"lncRNA", "apoptosis", "WRKY"

zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.

J. Cell Biol.1993 Dec;123(6 Pt 2):1727-34. doi:10.1083/jcb.123.6.1727
O Kuge 1 , S Hara-Kuge , L Orci , M Ravazzola , M Amherdt , G Tanigawa , F T Wieland , J E Rothman
O Kuge 1 , S Hara-Kuge , L Orci , M Ravazzola , M Amherdt , G Tanigawa , F T Wieland , J E Rothman
+ et al

[No authors listed]

Author information
  • 1 Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York 10021.

摘要


cDNA encoding the 20-kD subunit of coatomer, zeta-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to zeta-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (beta-, beta'-, gamma-, and epsilon-COP), zeta-COP exists in both coatomer bound and free pools.