cDNA cloning and expression of bovine endothelin converting enzyme.
Biochem. Biophys. Res. Commun.1994 Sep 30;203(3):1417-22
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摘要
We have cloned cDNA encoding bovine endothelin converting enzyme (ECE). The predicted amino acid sequence of bovine ECE consisted of 758 amino acid residues. Northern blot analysis revealed that ECE mRNA was abundantly expressed in lung. Co-expression of the cloned cDNA of bovine ECE with human preproET-1 cDNA in CHO-K1 cells resulted in the production of mature ET-1 and this production was inhibited by phosphoramidon.
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基因功能
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原始数据
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文献解读
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