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Assignment of superoxide dismutase (SOD-1) gene to chromosome No. 9 of domestic pig.

Can. J. Genet. Cytol.1983 Jun;25(3):233-8. doi:10.1139/g83-037
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摘要


Pig--mouse somatic cell hybrids were obtained by fusing pig lymphocytes with mouse cells of the RAG (HPTR-) line using polyethylene glycol. The expression of pig superoxide dismutase (SOD-1) activity in 11 hybrid clones as well as in the parental cells was investigated. Seven hybrid clones positive for the expression of pig SOD-1 displayed the corresponding parental RAG and pig bands of SOD-1 plus a heteropolymeric band of intermediate electrophoretic mobility. The positive and negative expression of pig SOD-1 was concordant with the retention and loss of pig chromosome No. 9, suggesting that the gene for pig SOD-1 is located on the chromosome No. 9 of the domestic pig.

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