[PTX3 promotes proliferation, invasion and drug resistance of neuroblastoma cells in children by regulating TLR4/NF-ÎºB signaling pathway].

Zhonghua Zhong Liu Za Zhi. 2021 Jan 23;43(1):118-125. doi:10.3760/cma.j.cn112152-20191227-00844

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Inhibition of PTX3 can inhibit the proliferation and invasion of neuroblastoma cells SH-SY5Y, and reduce drug resistance. Its mechanism may be achieved by regulating the TLR4/NF-ÎºB signaling pathway. This result can provide a new perspective for pediatric neuroblasts tumor diagnosis and clinical treatment.

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[PTX3 promotes proliferation, invasion and drug resistance of neuroblastoma cells in children by regulating TLR4/NF-ÎºB signaling pathway].

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