PARPs' impact on base excision DNA repair.
DNA Repair (Amst). 2020 Sep;93:102911
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摘要
Poly(ADP-ribosyl)ation is one of immediate cellular responses to DNA damage and is catalyzed by poly(ADP-ribose) polymerases is a well-known regulator of DNA repair. Another member of this family, was discovered later. The study of Pduanyu371 and functions started a long time ago, and special attention has been given to the role of these enzymes in base excision repair. This review summarizes my lab's data on the functions of Pduanyu371 and Pduanyu372 in base excision repair as well as the results obtained in the course of our collaboration with Dr. Samuel H. Wilson.
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基因功能
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原始数据
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文献解读
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