The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics.
Trends Immunol. 2020 Nov;41(11):965-967. Epub 2020 Sep 23
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摘要
The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a significant global health challenge. A recent study by Carvelli and colleagues now demonstrates the involvement of complement C5a and its receptor C5aR1 in disease progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential therapeutic strategy against COVID-19.
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文献解读
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