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A curious case of cysteines in human peroxiredoxin I.

Redox Biol. 2020 Oct;37:101738. Epub 2020 Sep 24
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摘要


was resistant to hyperoxidation and formation of stable high molecular weight oligomers, which is suggestive of impaired chaperone activity. Our results suggest that the catalytic residues of hPrxI are essential to counter the nitrosative stress whereas Cys83 in hPrxI plays a critical role in hyperoxidation of hPrxI.

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