例如:"lncRNA", "apoptosis", "WRKY"

C1 esterase inhibitor and the contact system in COVID-19.

Br J Haematol. 2020 Aug;190(4):520-524. doi:10.1111/bjh.16938. Epub 2020 Jul 28
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摘要


Coronavirus disease 2019 (COVID-19) is frequently associated with severe systemic consequences, including vasculitis, a hyperinflammatory state and hypercoagulation. The mechanisms leading to these life-threatening abnormalities are multifactorial. Based on the analysis of publicly available interactomes, we propose that severe acute respiratory syndrome coronavirus-2 infection directly causes a deficiency in C1 esterase inhibitor, a pathogen-specific mechanism that may help explain significant systemic abnormalities in patients with COVID-19. © 2020 British Society for Haematology and John Wiley & Sons Ltd.

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