例如:"lncRNA", "apoptosis", "WRKY"

DHH1/DDX6-like RNA helicases maintain ephemeral half-lives of stress-response mRNAs.

Nat Plants. 2020 Jun;6(6):675-685. Epub 2020 Jun 01
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摘要


Gene transcription is counterbalanced by messenger RNA decay processes that regulate transcript quality and quantity. We show here that the evolutionarily conserved DHH1/DDX6-like RNA hellicases of Arabidopsis thaliana control the ephemerality of a subset of cellular mRNAs. These RNA helicases co-localize with key markers of processing bodies and stress granules and contribute to their subcellular dynamics. They function to limit the precocious accumulation and ribosome association of stress-responsive mRNAs involved in auto-immunity and growth inhibition under non-stress conditions. Given the conservation of this RNA helicase subfamily, they may control basal levels of conditionally regulated mRNAs in diverse eukaryotes, accelerating responses without penalty.

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基因功能


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