Glial Fibrillary Acidic Protein in the Diagnosis and Prognosis of Malignant Glial Tumors.
Bull Exp Biol Med. 2020 Feb;168(4):503-506. Epub 2020 Mar 09
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摘要
Serum levels of glial fibrillar acidic protein (GFAP) were analyzed in 317 patients with primary and metastatic tumors of the brain, 78 patients with neurological diseases, and 66 normal subjects. A significant increase in the basal level of GFAP was typical of patients with glioblastomas in comparison with other groups (patients with astrocytomas, cerebral metastases, benign tumors, non-tumor diseases, and healthy subjects). An association of GFAP levels with unfavorable prognosis of overall survival in patients with glioblastoma was revealed. The data attest to high specificity and sensitivity of GFAP as a biochemical marker of glioblastoma.
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基因功能
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原始数据
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文献解读
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