CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.
EMBO Rep. 2020 Mar 04;21(3):e48512. doi:10.15252/embr.201948512. Epub 2020 Jan 09
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摘要
mice display ASD-related social behavior changes in the early postnatal period as well as in adults. Together, we demonstrate that CRMP2 mediates Sema3F-dependent synapse pruning and its dysfunction shares histological and behavioral features of ASD.
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基因功能
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原始数据
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文献解读
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