T Helper 9 Cells: A New Player in Immune-Related Diseases.
DNA Cell Biol.2019 Oct;38(10):1040-1047. doi:10.1089/dna.2019.4729. Epub 2019 Aug 16
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摘要
The helper T cell 9 (Thelper-9, Th9), as a functional subgroup of CD4+T cells, was first discovered in 2008. Th9 cells expressed transcription factor PU.1 and cytokine interleukin-9 (IL-9) characteristically. Recent researches have shown that the differentiation of Th9 cells was coregulated by cytokine transforming growth factor β, IL-4, and various transcription factors. Th9 cells, as a new player, played an important role in various immune-related diseases, including tumors, inflammatory diseases, parasite infection, and other diseases. In this article, we summarize the related research progress and discuss the possible prospect.
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基因功能
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文献解读
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