Study of dCTCF Insulator Activity in Drosophilamelanogaster Model Systems.
Dokl. Biochem. Biophys.2019 May;486(1):187-191. Epub 2019 Jul 31
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摘要
Using transgenic Drosophila model systems, we showed that four binding sites for the architectural protein dCTCF per se cannot form an effective insulator that blocks enhancers and protects against the Polycomb-dependent repression. These results suggest that, in the known Drosophila insulators, the dCTCF protein functions in cooperation with other architectural proteins.
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基因功能
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原始数据
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文献解读
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