例如："lncRNA", "apoptosis", "WRKY"

Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease.

J. Interferon Cytokine Res.2019 Aug;39(8):472-482. doi:10.1089/jir.2018.0154. Epub 2019 Jun 13
Shan Tong 1 , Qingwei Ji 2 , Yu Du 3 , Xiaogang Zhu 3 , Caizhong Zhu 1 , Yujie Zhou 3
Shan Tong 1 , Qingwei Ji 2 , Yu Du 3 , Xiaogang Zhu 3 , Caizhong Zhu 1 , Yujie Zhou 3
+ et al

[No authors listed]

Author information
  • 1 2Department of Geriatric Medicine and Gerontology, Hainan General Hospital, Hainan, China.
  • 2 3Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • 3 1Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Department of Cardiology, 12th ward, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, China.

摘要

Adipose tissue stores energy and is the largest endocrine organ in the body, producing several adipokines. However, among these adipokines, few play a role in the positive metabolism that promotes good health. Secreted frizzled-related protein (Sfrp)-5, an antagonist that directly binds to Wnt, has attracted interest due to its favorable effects on atherosclerotic cardiovascular disease (ASCVD). This review focuses on Sfrp5 biology and the roles of the Sfrp5/Wnt system in ASCVD.

KEYWORDS: Sfrp5, Wnt signaling pathway, adipokines, atherosclerotic cardiovascular disease

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