The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.
PLoS ONE. 2019 May 20;14(5):e0217002. eCollection 2019
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摘要
CONCLUSIONS:These findings provide further evidence that DLL1 exerts carcinogenic effects in BC cells. The dissimilar effects of DLL1 downregulation observed amongst MCF-7, BT474, and MDA-MB-231 cells is likely due to their distinctive genetic and biologic characteristics, suggesting that DLL1 contributes to BC through various mechanisms.
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基因功能
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原始数据
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文献解读
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