Clinical and pathological significance of Homo sapiens ceramide synthase 2 (CerS-2) in diverse human cancers.
Biosci Rep. 2019 May 07;39(5)
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摘要
Homo sapiens ceramide synthase 2 (CerS-2) plays an important role in inhibiting invasion and metastasis of tumor cells and has been reported as a tumor metastasis suppressor gene in diverse cancers. Thus, low level of CerS-2 protein might suggest a bad prognosis and up-regulation of CerS-2 protein might act as a promising therapeutic strategy for malignant tumors. In this review, we discussed the expression, as well as the clinical and pathological significance of CerS-2 in diverse human cancers. The pathological processes and molecular pathways regulated by CerS-2 were also summarized.
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基因功能
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原始数据
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文献解读
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