An end in sight? Xrn2 and transcriptional termination by RNA polymerase II.
Transcription. 2018;9(5):321-326. doi:10.1080/21541264.2018.1498708. Epub 2018 Aug 02
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摘要
Every transcription cycle ends in termination when RNA polymerase dissociates from the DNA. Although conceptually simple, the mechanism has proven somewhat elusive in eukaryotic systems. Gene-editing and high resolution polymerase mapping now offer clarification of important steps preceding transcriptional termination by RNA polymerase II in human cells.
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文献解读
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