Structural analysis of a new GC-specific insertion element IS186.

FEBS Lett.1985 Nov 11;192(1):47-52

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摘要

A new insertion sequence, IS186, has been identified from Escherichia coli and sequenced. It contains 1336 base pairs with a terminal inverted repeat of 22 nucleotides. A long open reading frame, from an ATG codon at position 55 to a TAG termination codon at 1327, could code for a polypeptide of 424 amino acids. This element recognizes GC-rich regions as target sites for insertion.

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Structural analysis of a new GC-specific insertion element IS186.

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