Insulator Protein Su(Hw) Is Indispensable for Amplification of Part of Drosophila Amplicons in Follicular Cells (DAFCs) during Early Oogenesis.
Dokl. Biochem. Biophys.2018 Mar;479(1):80-82. Epub 2018 May 19
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摘要
We found that the Su(Hw) insulator protein binds to all known Drosophila amplicons in follicular cells (DAFCs). Su(Hw) binding is required for ORC replication complex positioning on part of DAFCs during early oogenesis. Our data allow us to expand the current view on the role of the Su(Hw) protein in Drosophila oogenesis as a transcription repressor. We assume that Su(Hw) is involved in the coordination of transcription and replication processes during oogenesis in Drosophila.
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基因功能
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原始数据
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文献解读
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