Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

Neurosci. Res.2018 Oct;135:13-20. Epub 2018 Mar 31

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mice, the length of the AnkyrinG-positive region shortened and somatic organelles leaked into the axons. These results suggested that exon 34 of AnkyrinG is an embryonic-stage-preferential exon that should be excluded from mature neurons and that Elavl3 regulates neuronal polarity through alternative splicing of this exon.

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Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

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