Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.

Development. 2018 Jan 17;145(2)

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摘要

conditional knockout, we show that netrin 1, which is released at the pial surface by ventricular zone progenitors is responsible for the CNS confinement of precerebellar neurons. We propose, that netrin 1 distribution sculpts the CNS boundary by keeping CNS neurons in netrin 1-rich domains.

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Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.

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