Sharing the load: Mex67-Mtr2 cofunctions with Los1 in primary tRNA nuclear export.

Genes Dev.2017 Nov 01;31(21):2186-2198. Epub 2017 Dec 06

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Î cells. Moreover, in vivo coimmunoprecipitation assays with tagged Mex67 document that the Mex67 binds tRNAs. Our data also show that tRNA exporters surprisingly exhibit differential tRNA substrate preferences. The existence of multiple tRNA exporters, each with different tRNA preferences, may indicate that the proteome can be regulated by tRNA nuclear export. Thus, our data show that Mex67-Mtr2 functions in primary nuclear export for a subset of yeast tRNAs.

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Sharing the load: Mex67-Mtr2 cofunctions with Los1 in primary tRNA nuclear export.

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