TYRP1 mRNA goes fishing for miRNAs in melanoma.
Nat. Cell Biol.2017 Oct 31;19(11):1311-1312
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摘要
A variety of non-coding RNAs have been reported as endogenous sponges for cancer-modulating miRNAs. However, miRNA trapping by transcripts with protein-coding functions is less understood. The mRNA of TYRP1 is now found to sequester the tumour suppressor miR-16 on non-canonical miRNA response elements in melanoma, thereby promoting malignant growth.
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基因功能
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原始数据
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文献解读
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