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Clamping down on drugs: the Escherichia coli multidrug efflux protein MdtM.

Res. Microbiol.2018 Sep - Oct ;169(7-8):461-467. Epub 2017 Sep 27
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摘要


Multidrug resistance is principally a consequence of the active transport of drugs out of the cell by proteins that are integral membrane transporters. In the following review, we present a synthesis of current understanding of the Escherichia coli multidrug resistance transporter, MdtM, a 410 amino acid residue protein that belongs to the large and ubiquitous major facilitator superfamily (MFS).

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