Interferon-omega: Current status in clinical applications.
[No authors listed]
摘要
Since 1985, interferon (IFN)-Ï, a type I IFN, has been identified in many animals, but not canines and mice. It has been demonstrated to have antiviral, anti-proliferation, and antitumor activities that are similar to those of IFN-α. To date, IFN-Ï has been explored as a treatment option for some diseases or viral infections in humans and other animals. Studies have revealed that human IFN-Ï displays antitumor activities in some models of human cancer cells and that it can be used to diagnose some diseases. While recombinant feline IFN-Ï has been licensed in several countries for treating canine parvovirus, feline leukemia virus, and feline immunodeficiency virus infections, it also exhibits a certain efficacy when used to treat other viral infections or diseases. This review examines the known biological activity of IFN-Ï and its clinical applications. We expect that the information provided in this review will stimulate further studies of IFN-Ï as a therapeutic agent.
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基因功能
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文献解读
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