uniporter (MCU) complex and enhances gemcitabine apoptotic effect in pancreatic cancer.
Cancer Lett.2017 Dec 28;411:106-116. Epub 2017 Sep 23
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摘要
influx through the mitochondrial calcium uniporter (MCU). In addition, we found that HINT2 can sensitize BxPC-3 and L3.6pl cells to gemcitabine-induced apoptosis and that gemcitabine up-regulates HINT2 expression. This indicates that gemcitabine-induced apoptosis is related to HINT2 levels.
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基因功能
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文献解读
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