Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells.
Metallomics. 2017 Oct 18;9(10):1389-1393. doi:10.1039/c7mt00254h
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摘要
, iron loading with ferric ammonium citrate (FAC) had the opposite effect. Taken together, the study reveals a gain-of-function phenotype for Dcytb rs10455 mutation that could be a putative modifier of colorectal cancer risk, with attendant variability in penetrance among human HFE C282Y homozygotes.
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基因功能
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原始数据
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文献解读
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