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A bioactive peptide amidating enzyme is required for ciliogenesis.

Elife. 2017 May 17;6. doi:10.7554/eLife.25728
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摘要


mouse embryos was also aberrant. Our data suggest that PAM activity and alterations in post-Golgi trafficking contribute to the observed ciliogenesis defects and provide an unanticipated, highly conserved link between PAM, amidation and ciliary assembly.

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