P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo.

Stem Cell Res. 2017 May;21:141-147. Epub 2017 May 03

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mouse to test whether the RSC population is affected by the loss of P-Cadherin expression, our experiments demonstrate that the RSCs reside in the pigmented CE layer and express P-Cadherin, which is important to the formation of adherent sphere colonies in vitro, however P-Cadherin is not required for maintenance of RSCs in vivo.

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P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo.

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