[No authors listed]
BACKGROUND: in colorectal cancer remains unclear. METHODS: in human colorectal cancer, we studied ten colorectal cancer cell lines and 146 primary colorectal cancer samples and 50 matched adjacent samples using semi-quantitative reverse transcription PCR, immunohistochemistry, methylation-specific PCR and bisulfite sequencing, western blot, flow cytometry, and transwell assays. RESULTS: suppressed colorectal cancer cell xenograft growth in nude mice. CONCLUSIONS: is a marker of poor prognosis in human colorectal cancer.
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