例如："lncRNA", "apoptosis", "WRKY"

Toll-like receptor 2 gene polymorphisms in Chinese Holstein cattle and their associations with bovine tuberculosis.

Vet. Immunol. Immunopathol.2017 Apr;186:51-54. Epub 2017 Feb 28
Zhanqin Zhao 1 , Yun Xue 2 , Zhigang Hu 3 , Feng Zhou 4 , Beibei Ma 4 , Ta Long 4 , Qiao Xue 4 , Huisheng Liu 4
Zhanqin Zhao 1 , Yun Xue 2 , Zhigang Hu 3 , Feng Zhou 4 , Beibei Ma 4 , Ta Long 4 , Qiao Xue 4 , Huisheng Liu 4
+ et al

[No authors listed]

Author information
  • 1 Lab of Veterinary Microbiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China; Lab of Medical Engineering, College of Medical Technology and Engineering, Henan University of Science and Technology, No. 31 Anhui Road, Luoyang 471003, China.
  • 2 Lab of Medical Engineering, College of Medical Technology and Engineering, Henan University of Science and Technology, No. 31 Anhui Road, Luoyang 471003, China. Electronic address: xueyun6688@163.com.
  • 3 Lab of Medical Engineering, College of Medical Technology and Engineering, Henan University of Science and Technology, No. 31 Anhui Road, Luoyang 471003, China.
  • 4 Lab of Veterinary Microbiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.

摘要

This study evaluated whether there was an association between polymorphisms within the Toll-like receptor 2 gene (TLR2) of Chinese Holstein cattle and susceptibility to bovine tuberculosis (BTB). In a case-control study including 210 BTB cases and 237 control cattle, we found only two common single-nucleotide polymorphisms (SNPs) within the entire coding region of the TLR2 gene, A631G (rs95214857) and T1707C (rs1388116488). Additionally, the allele and genotype distributions of A631G and T1707C were not different between case and control groups, indicated that these SNPs were not associated with susceptibility to BTB. These results suggested that polymorphisms in the TLR2 gene might not play a significant role in the BTB risk in Chinese Holstein cattle.

KEYWORDS: Bovine tuberculosis, Chinese Holstein cattle, Single-nucleotide polymorphisms, Toll-like receptor 2 gene

© 2017 biocloud.net版权所有 ICP证：京10042835号