Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.

Calcif. Tissue Int.2017 Aug;101(2):207-216. Epub 2017 Apr 07

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; pâ<â0.05), as were nuclear size and the surface area of cytoplasm. The nuclei of adseverin null osteoclasts exhibited more heterochromatin (31âÂ±â3%) than wild-type cells (8âÂ±â1%), suggesting that adseverin affects cell differentiation. The data indicate that in healthy, developing tissues, adseverin contributes to the regulation of osteoclast structure but not to bone metabolism in vivo.

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Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.

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