MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes.

Oncogene. 2017 Jul 27;36(30):4311-4322. Epub 2017 Mar 27

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overexpression. Taken together, our findings indicate that MRL proteins cooperate with oncogenic Ras to promote formation of glial tumours, and that, in this context, Mal/serum response factor activation is rate-limiting for tumour dissemination.

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MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes.

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