A critical role of solute carrier 22a14 in sperm motility and male fertility in mice.

Sci Rep. 2016 Nov 04;6:36468

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sperm cells: the annulus, a ring-like structure at the mid-piece-principal piece junction, was disorganised, and expression and localisation of septin 4, an annulus component protein that is essential for the annulus formation, was also impaired. Taken together, our results demonstrated that Slc22a14 plays a pivotal role in normal flagellar structure, motility and fertility in mouse spermatozoa.

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A critical role of solute carrier 22a14 in sperm motility and male fertility in mice.

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