Zinc finger domain of Su(Hw) protein is required for the formation of functional Su(Hw)-dependent insulator complex.
Dokl. Biochem. Biophys.2016 Jul;469(1):247-52. Epub 2016 Sep 07
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摘要
This study is devoted to clarifying the role of Mod(mdg4)-67.2 and Su(Hw) proteins in the interaction between Su(Hw)-dependent insulator complexes and identifying the specific domains of the Su(Hw) protein required for insulation or mutual neutralization of insulators. Using genetic techniques and experiments in yeast two-hybrid system, we have demonstrated that the zinc finger domain of the Su(Hw) protein is involved in forming a functional insulator complex and cannot be replaced with the DNA-binding domain of the GAL4 protein.
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基因功能
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原始数据
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文献解读
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