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A Guardian Angel Phosphatase for Mainline Carbon Metabolism.

Trends Biochem. Sci.2016 Nov;41(11):893-894. Epub 2016 Aug 17
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摘要


It is increasingly clear that many metabolic enzymes mistakenly form minor but toxic side-products that must be eliminated to maintain normal fluxes. Collard et al. show that this is true of two iconic glycolytic enzymes, and that a hitherto somewhat mysterious phosphatase rescues central carbon metabolism from their mistakes.

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