Structure determination of transient transcription complexes.

Biochem. Soc. Trans.2016 Aug 15;44(4):1177-82

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The determination of detailed 3D structures of large and transient multicomponent complexes remains challenging. Here I describe the approaches that were used and developed by our laboratory to achieve structure solution of eukaryotic transcription complexes. I hope this collection serves as a resource for structural biologists seeking solutions for difficult structure determination projects.

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Structure determination of transient transcription complexes.

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