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Does Unc-GFP uncover ciliary structures in the rhabdomeric eye of Drosophila?

J. Cell. Sci.2016 Jul 15;129(14):2726-31. Epub 2016 May 27
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摘要


The uncoordinated (unc) gene product, a potential ortholog of mammalian orofaciodigital syndrome 1 (Ofd1), is involved in the assembly of the ciliary axoneme in Drosophila and it is, therefore, constrained to cell types that have ciliary structures, namely type 1 sensory neurons and male germ cells. Here, we show that evenly spaced Unc-GFP spots are present in the eye imaginal discs of third-instar larvae. These spots are restricted to the R8 photoreceptor cell of each ommatidium in association with mother centrioles. This finding is unexpected because the Drosophila eye is of the rhabdomeric type and would be expected to lack ciliary structures.

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