Polycystic Kidney Disease: Lessons Learned from Caenorhabditis elegans Mating Behavior.
Curr. Biol.2015 Dec 21;25(24):R1168-70
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摘要
Male worm mating requires lov-1 and pkd-2 (homologs of the human polycystic kidney disease genes, PKD1 and PKD2), which are expressed in male-specific neurons. Transcriptomic analysis of these neurons now catalogs molecules involved in signaling and ectosome biogenesis, with implications for human PKD.
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基因功能
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原始数据
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文献解读
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