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The Impact of UNC5C Genetic Variations on Neuroimaging in Alzheimer's Disease.

Mol. Neurobiol.2016 Dec;53(10):6759-6767. Epub 2015 Dec 11
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摘要


 = 0.0055). UNC5C genotypes were significantly associated with the volume of the middle temporal on MRI; meanwhile, UNC5C loci could alter the atrophy of strategic regions of AD such as the hippocampus and precuneus. And the above effects of polymorphisms of UNC5C were more obvious in the population with the impaired cognition than those with the normal cognition.

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