例如:"lncRNA", "apoptosis", "WRKY"

A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development.

Nat Commun. 2015 Nov 18;6:8821
Qian Chen 1 , Yang Liu 2 , Steven Maere 3 , Eunkyoung Lee 4 , Gert Van Isterdael 3 , Zidian Xie 5 , Wei Xuan 3 , Jessica Lucas 4 , Valya Vassileva 6 , Saeko Kitakura 7 , Peter Marhavý 8 , Krzysztof Wabnik 9 , Niko Geldner 8 , Eva Benková 9 , Jie Le 10 , Hidehiro Fukaki 11 , Erich Grotewold 5 , Chuanyou Li 1 , Jiří Friml 9 , Fred Sack 4 , Tom Beeckman 3 , Steffen Vanneste 3
Qian Chen 1 , Yang Liu 2 , Steven Maere 3 , Eunkyoung Lee 4 , Gert Van Isterdael 3 , Zidian Xie 5 , Wei Xuan 3 , Jessica Lucas 4 , Valya Vassileva 6 , Saeko Kitakura 7 , Peter Marhavý 8 , Krzysztof Wabnik 9 , Niko Geldner 8 , Eva Benková 9 , Jie Le 10 , Hidehiro Fukaki 11 , Erich Grotewold 5 , Chuanyou Li 1 , Jiří Friml 9 , Fred Sack 4 , Tom Beeckman 3 , Steffen Vanneste 3
+ et al

[No authors listed]

Author information
  • 1 State Key Laboratory of Plant Genomics, National Centre for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
  • 2 Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
  • 3 Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent 9052, Belgium.
  • 4 Department of Botany, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.
  • 5 Center for Applied Plant Sciences (CAPS) and Department of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210, USA.
  • 6 Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, Academik Georgi Bonchev Street, Sofia 1113, Bulgaria.
  • 7 Department of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043 Japan.
  • 8 Department of Plant Molecular Biology, UNIL-Sorge, University of Lausanne, Lausanne 1015, Switzerland.
  • 9 Institute of Science and Technology Austria, Klosterneuburg 3400, Austria.
  • 10 Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China.
  • 11 Department of Biology, Graduate School of Science, Kobe University, 1-1 Rokkodai, Kobe 657-8501, Japan.

摘要


Multiple plant developmental processes, such as lateral root development, depend on auxin distribution patterns that are in part generated by the PIN-formed family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7 (ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation. This regulatory mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli, potentially maintaining and enhancing the robustness of the auxin flux directionality during lateral root development. The cooperative action between canonical auxin signalling and other transcription factors might constitute a general mechanism by which transcriptional auxin-sensitivity can be regulated at a tissue-specific level.