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Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron.

Am. J. Physiol. Renal Physiol.2015 Sep 15;309(6):F489-91. Epub 2015 Jul 01
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摘要


The electrogenic Na(+)-HCO3 (-) cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K(+) and Ca(2+) transport in the distal nephron.

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