Yvh1 protein phosphatase is required for pre-autophagosomal structure formation after TORC1 inactivation.

Biosci. Biotechnol. Biochem.2015;79(12):2022-5. doi:10.1080/09168451.2015.1060846. Epub 2015 Jun 30

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The pre-autophagosomal structure (PAS) is a putative site for autophagosome formation in budding yeast. Upon nutrient depletion or rapamycin treatment, target of rapamycin complex 1 (TORC1) becomes inactive, inducing PAS formation and autophagy. Here, we show that Yvh1 phosphatase is critical for PAS formation, but not autophagy induction, after TORC1 inactivation.

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Yvh1 protein phosphatase is required for pre-autophagosomal structure formation after TORC1 inactivation.

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