[Genetic studies of primary open-angle glaucoma].

Vestn Oftalmol. 2014 Sep-Oct ;130(5):96-9

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The present review is devoted to genetic studies of primary open-angle glaucoma (POAG). Today, POAG is considered a multifactorial disease with threshold effect, which is associated with single or multiple genes mutation as well as external influences. According to molecular genetic studies, three causative genes (MYOC, optinevrin, WDR 36) and several dosens of candidate genes are involved in the development of POAG.

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[Genetic studies of primary open-angle glaucoma].

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