Electrochemically driven drug metabolism via a CYP1A2-UGT1A10 bienzyme confined in a graphene nano-cage.
Chem. Commun. (Camb.). 2014 Nov 21;50(90):13896-9. doi:10.1039/c4cc06200k
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摘要
A graphene nano-cage with regulatable space for the assembly of a cytochrome P450 1A2-UDP-glucuronosyltransferase 1A10 bienzyme complex has been constructed via a click reaction, and successfully used to study drug sequential metabolism using an electrochemically-driven method.
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基因功能
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原始数据
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文献解读
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