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Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism.

Chembiochem. 2014 May 26;15(8):1079-81. doi:10.1002/cbic.201402095. Epub 2014 Apr 25
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摘要


ACP captured in action: Two recently reported crystal structures are the first to capture ACP-mediated substrate delivery to a catalytic partner at high resolution. These studies highlight key interactions of transient ACP-partner complexes and define the dynamic movements of ACP that facilitate substrate delivery and trigger complex dissociation.

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